Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749460 | 0.63 | — | — | |
| SCHEMBL24188741 | 0.59 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL21769502 | 0.59 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL24192726 | 0.57 | THRB (0.43) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL24408065 | 0.56 | THRB (0.40) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL24193214 | 0.56 | HPGD (0.37) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL22924681 | 0.54 | — | — | |
| SCHEMBL16849208 | 0.53 | — | — | |
| SCHEMBL22626700 | 0.53 | — | — | |
| SCHEMBL4896144 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141027-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREOF AND USE THEREOF | 南京华威医药科技集团有限公司 | 2019-07-25 | — | — | WO | disclosed |