Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL7180336 | 0.89 | MAPT (0.43) | MAPTTDP1LMNASMN1; SMN2NLRP3 | |
| P-Xylene SCHEMBL223418 | 0.87 | HPGD (0.46) | MAPTTDP1LMNAHPGDNLRP3 | |
| P-Xylene SCHEMBL11573033 | 0.82 | NLRP3 (0.50) | MAPTLMNASMN1; SMN2NLRP3MEN1 | |
| Acetic Acid Butyl Ester SCHEMBL3407993 | 0.79 | ALDH1A1 (0.51) | MAPTTDP1LMNASMN1; SMN2HPGD | |
| SCHEMBL166674 | 0.76 | DGKA (0.50) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| Toluene SCHEMBL28111602 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL2044080 | 0.74 | GAA (0.52) | MAPTTDP1LMNASMN1; SMN2TSHR | |
| SCHEMBL29075 | 0.74 | — | — | |
| O-Xylene SCHEMBL27841634 | 0.74 | ALDH1A1 (0.49) | LMNASMN1; SMN2HPGDNLRP3TSHR | |
| SCHEMBL1871750 | 0.73 | KMT2A (0.56) | MAPTTDP1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095164-A1 | CROSSLINKABLE POLYURETHANE DISPERSIONS | BAYER MATERIALSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-7691941-B2 | Low-solvent or solvent-free crosslinker dispersions with pyrazole-blocked isocyanate groups | BAYER MATERIAL SCIENCE AG (DE) | 2010-04-06 | — | — | US | disclosed |
| US-7589148-B2 | Preparation of a polyurethane dispersion with blocked isocyanate groups | BAYER MATERIALSCIENCE AG (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20080161487-A1 | Cosolvent-free, self-crosslinking PU dispersions | BAYER MATERIALSCIENCE AG | 2008-07-03 | — | — | US | disclosed |
| US-20070282062-A1 | Low-solvent or solvent-free crosslinker dispersions with pyrazole-blocked isocyanate groups | BAYER MATERIALSCIENCE AG | 2007-12-06 | — | — | US | disclosed |
| US-20070265389-A1 | Aqueous dispersions with bimodal particle size distribution | BAYER MATERIALSCIENCE AG (DE) | 2007-11-15 | — | — | US | disclosed |
| US-20070129488-A1 | Preparation of a polyurethane dispersion with blocked isocyanate groups | BAYER MATERIALSCIENCE AG | 2007-06-07 | — | — | US | disclosed |
| US-20070032594-A1 | Self-crosslinking polyurethane dispersions containing uretdione and isocyanate-reactive groups | BAYER MATERIALSCIENCE AG | 2007-02-08 | — | — | US | disclosed |
| US-20070004894-A1 | Silicon-free polyisocyanate or polyurethanes having monoamide-containing hydrophilic groups | BAYER MATERIALSCIENCE AG | 2007-01-04 | — | — | US | disclosed |
| US-6583216-B1 | Crosslinking agents are storage stable with little yellowing; 1,6-diisocyanatohexane blocked with diethyl malonate, 1-amino-3,3,5- trimethyl-5-aminomethylcyclohexane, and formaldehyde | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-24 | — | — | US | disclosed |
| US-6335381-B1 | AQUEOUS COATING COMPOSITION COMPRISING REACTION PRODUCT OF POLYISOCYANATE AND MONOHYDRIC ALCOHOL HAVING (METH)ACRYLOYL GROUPS, ULTRAVIOLET RADIATION INITIATOR WHICH INITIATES POLYMERIZATION BY FREE RADICAL MECHANISM, REACTIVE BINDER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |