Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177456 | 0.95 | POLB (0.58) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL10711348 | 0.90 | HTT (0.56) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL30073423 | 0.89 | KMT2A (0.60) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL15285967 | 0.89 | KMT2A (0.60) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL17502635 | 0.87 | KMT2A (0.65) | KMT2AALDH1A1KDM4EGAAPOLB | |
| SCHEMBL1505357 | 0.86 | ALDH1A1 (0.62) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL1505252 | 0.83 | ALDH1A1 (0.60) | KMT2AGLAALDH1A1KDM4EGAA | |
| SCHEMBL5255412 | 0.82 | RAB9A (0.61) | KMT2AKDM4EGAARAB9AMAPT | |
| SCHEMBL29717082 | 0.81 | RAB9A (0.57) | KMT2AKDM4EGAAPOLBRAB9A | |
| SCHEMBL21177330 | 0.80 | KMT2A (0.47) | KMT2AGLAALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141694-A1 | PI4KIIIBETA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-25 | — | — | WO | disclosed |