Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502635 | 0.94 | KMT2A (0.65) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21189595 | 0.90 | KMT2A (0.64) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL21813217 | 0.85 | L3MBTL3 (0.52) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21177456 | 0.85 | POLB (0.58) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL21189571 | 0.83 | DRD2 (0.47) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30514816 | 0.83 | DRD2 (0.47) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30514833 | 0.83 | DRD2 (0.47) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21177413 | 0.82 | KMT2A (0.44) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15286110 | 0.82 | ALDH1A1 (0.61) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17502632 | 0.81 | MEN1 (0.65) | HTTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124476-B1 | CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |
| US-4559349-A | TREATMENT OF PHYCHOSIS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0124476-A1 | Carboxamides, process for their preparation and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | disclosed |