Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880763 | 0.90 | KMT2A (0.40) | KMT2AMEN1HPGDHTTROCK1 | |
| SCHEMBL2798855 | 0.90 | HPGD (0.46) | KMT2AMEN1HPGDHTTTSHR | |
| SCHEMBL21189713 | 0.86 | TSHR (0.46) | KMT2AMEN1HPGDTSHRROCK1 | |
| SCHEMBL12795963 | 0.85 | TSHR (0.49) | KMT2AMEN1HPGDTSHRROCK1 | |
| SCHEMBL24340135 | 0.84 | HSP90AA1 (0.43) | KMT2AMEN1HPGDTSHRROCK1 | |
| SCHEMBL21177333 | 0.84 | ROCK1 (0.38) | KMT2AMEN1HPGDHTTL3MBTL3 | |
| SCHEMBL21189459 | 0.84 | KMT2A (0.53) | KMT2AMEN1HPGDHTTTSHR | |
| SCHEMBL21177377 | 0.83 | RAB9A (0.42) | KMT2AMEN1L3MBTL3L3MBTL1ROCK1 | |
| SCHEMBL21177379 | 0.83 | RAB9A (0.42) | KMT2AMEN1L3MBTL3L3MBTL1ROCK1 | |
| SCHEMBL24745868 | 0.80 | HPGD (0.56) | KMT2AMEN1HPGDHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141694-A1 | PI4KIIIBETA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-25 | — | — | WO | disclosed |