Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177631 | 0.91 | POLB (0.54) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21189731 | 0.91 | POLB (0.53) | KMT2AGAAPOLBHTTNPC1 | |
| SCHEMBL24745868 | 0.89 | HPGD (0.56) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21812892 | 0.86 | L3MBTL3 (0.44) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21177182 | 0.85 | POLB (0.39) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21177386 | 0.84 | RAB9A (0.41) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21177388 | 0.84 | RAB9A (0.41) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21189725 | 0.84 | KMT2A (0.50) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL21189713 | 0.82 | TSHR (0.46) | KMT2AMEN1POLBNPC1HPGD | |
| SCHEMBL12795963 | 0.81 | TSHR (0.49) | KMT2AMEN1POLBNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141694-A1 | PI4KIIIBETA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-25 | — | — | WO | disclosed |