Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142702 | 0.90 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TTRCRHBPCRHR2 | |
| SCHEMBL15055488 | 0.84 | HSD17B10 (0.47) | ALDH1A1L3MBTL1TTRKMT2ATSHR | |
| SCHEMBL203768 | 0.83 | TTR (0.64) | ALDH1A1TTRKMT2AMAOAMAOB | |
| SCHEMBL30816847 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TTRCRHBPCRHR2 | |
| SCHEMBL6142767 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TTRCRHBPCRHR2 | |
| SCHEMBL30443455 | 0.83 | EPAS1 (0.55) | ALDH1A1L3MBTL1TTRKMT2AHSPB1 | |
| SCHEMBL15068219 | 0.83 | EPAS1 (0.55) | ALDH1A1L3MBTL1TTRKMT2AHSPB1 | |
| SCHEMBL21856167 | 0.82 | TTR (0.38) | ALDH1A1TTRKMT2ATSHRMEN1 | |
| SCHEMBL27689753 | 0.81 | PKM (0.47) | ALDH1A1L3MBTL1HSPB1TSHREPAS1 | |
| SCHEMBL2810532 | 0.81 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TTRCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |