Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.42 |
| ▸ | PDE4A | P27815 | 7/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191020 | 0.89 | BRD4 (0.52) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21190866 | 0.80 | IKBKE (0.46) | PDE4DPDE4APDE4BPDE4CSYK | |
| SCHEMBL21190864 | 0.80 | SYK (0.43) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21191141 | 0.78 | BRD4 (0.39) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21191018 | 0.78 | SYK (0.42) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL20789795 | 0.76 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL20789797 | 0.76 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL20154992 | 0.75 | HRH3 (0.41) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21190894 | 0.75 | BRD4 (0.51) | BRD4PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL16658440 | 0.74 | MAPT (0.43) | HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |