Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191020 | 0.87 | BRD4 (0.52) | BRD4PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21190903 | 0.85 | BRD4 (0.54) | BRD4 | |
| SCHEMBL21190898 | 0.80 | CSNK2A1 (0.48) | THRATHRBPOLBCSNK2A1PDE4B | |
| SCHEMBL21190896 | 0.80 | THRA (0.49) | THRATHRBPOLBCSNK2A1PDE4B | |
| SCHEMBL20443010 | 0.79 | POLB (0.49) | BRD4POLBMEN1KMT2ACYP19A1 | |
| SCHEMBL21190899 | 0.78 | CSNK2A1 (0.43) | THRATHRBPOLBCSNK2A1PDE4B | |
| SCHEMBL16335601 | 0.77 | RORC (0.47) | BRD4POLBPDE4BMEN1KMT2A | |
| SCHEMBL21191022 | 0.77 | BRD4 (0.50) | BRD4THRATHRBPDE4BPDE4A | |
| SCHEMBL21190876 | 0.76 | BRD4 (0.52) | BRD4THRATHRBPOLBPDE4B | |
| SCHEMBL21190895 | 0.76 | BRD4 (0.45) | BRD4CSNK2A1PDE4BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |