Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191018 | 0.86 | SYK (0.42) | CSNK2A1KMT2ANPY1RNPY2RGFER | |
| SCHEMBL21190906 | 0.84 | BRD4 (0.36) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL21190898 | 0.82 | CSNK2A1 (0.48) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL21190896 | 0.82 | THRA (0.49) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL21190894 | 0.78 | BRD4 (0.51) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL20443015 | 0.78 | KMT2A (0.43) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL12355729 | 0.76 | KMT2A (0.50) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL21191023 | 0.75 | HRH3 (0.39) | KMT2ATHRATHRBL3MBTL1GFER | |
| SCHEMBL20384189 | 0.75 | HPGD (0.43) | CSNK2A1KMT2AMEN1NPY1RNPY2R | |
| SCHEMBL3689787 | 0.74 | THRA (0.52) | KMT2AMEN1THRATHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |