Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21190898 | 0.87 | CSNK2A1 (0.48) | THRATHRBCSNK2A1RECQLMEN1 | |
| SCHEMBL8846224 | 0.85 | RECQL (0.55) | CSNK2A1RECQLALDH1A1TSHRPOLB | |
| SCHEMBL21190866 | 0.84 | IKBKE (0.46) | CSNK2A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15903786 | 0.83 | CSNK2A1 (0.47) | CSNK2A1RECQLALDH1A1TSHRPDE4A | |
| SCHEMBL21190899 | 0.82 | CSNK2A1 (0.43) | THRATHRBCSNK2A1RECQLMEN1 | |
| SCHEMBL15904183 | 0.81 | CSNK2A1 (0.48) | CSNK2A1RECQLALDH1A1TSHRPDE4A | |
| SCHEMBL10088511 | 0.81 | CSNK2A1 (0.72) | CSNK2A1RECQLALDH1A1TSHRMAPT | |
| SCHEMBL3721110 | 0.80 | THRA (0.41) | THRATHRBCSNK2A1MEN1KMT2A | |
| SCHEMBL21190894 | 0.80 | BRD4 (0.51) | THRATHRBCSNK2A1MEN1KMT2A | |
| SCHEMBL2958828 | 0.79 | RECQL (0.60) | RECQLPOLBPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |