SCHEMBL21192198

SCHEMBL21192198

CCSc1ncnc2c1ncn2C1OC(CO)C(O)C1O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 19/20 0.75
▸ STAT6 P42226 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15623875 1.00 SLC29A1 (0.75) SLC29A1STAT6
SCHEMBL6470152 1.00 SLC29A1 (0.75) SLC29A1STAT6
SCHEMBL6470156 1.00 SLC29A1 (0.75) SLC29A1STAT6
SCHEMBL3675456 1.00 SLC29A1 (0.75) SLC29A1STAT6
SCHEMBL7134319 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6
SCHEMBL30089484 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6
SCHEMBL672036 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6
SCHEMBL672035 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6
SCHEMBL240981 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6
SCHEMBL19488384 0.88 SMN1; SMN2 (0.77) SLC29A1STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190225643-A1 NOVEL NUCLEOSIDE ANALOGS AND USE THEREOF IN THERAPEUTIC TREATMENT CORNELL UNIVERSITY (US) 2019-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225643-A1 NOVEL NUCLEOSIDE ANALOGS AND USE THEREOF IN THERAPEUTIC TREATMENT DCK, NME4, ENTPD5 SLC29A1 80/4885STAT6 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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