Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309093 | 0.83 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL13955505 | 0.83 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL404146 | 0.83 | L3MBTL3 (0.35) | PYGL | |
| SCHEMBL21201850 | 0.80 | ADH1C (0.47) | PYGL | |
| SCHEMBL18893512 | 0.77 | PYGL (0.32) | PYGL | |
| SCHEMBL1307160 | 0.76 | PYGL (0.40) | PYGL | |
| SCHEMBL1712741 | 0.76 | PYGL (0.40) | PYGL | |
| SCHEMBL22830254 | 0.75 | HTR2A (0.37) | — | |
| SCHEMBL27788064 | 0.74 | ADH1C (0.33) | PYGL | |
| SCHEMBL1308424 | 0.74 | ADH1C (0.33) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190263828-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-08-29 | — | — | US | disclosed |
| US-10364255-B2 | Heteroaromatic compounds as Vanin inhibitors | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2019-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263828-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | VHL, FANCI, UGT2B7 | PYGL 1897/4885 |
| US-10364255-B2 | Heteroaromatic compounds as Vanin inhibitors | VHL, FANCI, UGT2B7 | PYGL 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.