Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 5/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119080 | 0.90 | ACLY (0.46) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2118430 | 0.90 | ALDH1A1 (0.44) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2118252 | 0.89 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2120606 | 0.89 | ACLY (0.54) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2120131 | 0.80 | ACLY (0.42) | ACLYHSD17B1HSD17B2ALDH1A1GAA | |
| SCHEMBL2118662 | 0.79 | ALDH1A1 (0.61) | HSD17B2ALDH1A1GAAGFERCYP2C9 | |
| SCHEMBL2118402 | 0.79 | TNF (0.44) | ACLYALDH1A1GAAGFERTSHR | |
| SCHEMBL2120558 | 0.78 | ACLY (0.45) | ACLYALDH1A1GAAGFERCYP11B1 | |
| SCHEMBL2120031 | 0.78 | ACLY (0.44) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2121424 | 0.78 | ALDH1A1 (0.52) | ACLYALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | TUBB4A 1564/4885TUBB 1824/4885TUBA3C 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.