SCHEMBL2120597

SCHEMBL2120597

Cc1ncc(CO)c(C)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 1/20 0.48
LMNA P02545 3/20 0.44
PDXK O00764 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
AOX1 Q06278 1/20 0.43
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
TKT P29401 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27911502 0.80 KDM4E (0.47) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL12186160 0.79 LMNA (0.42) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL15211577 0.78 PDXK (0.46) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL479344 0.78 LMNA (0.61) KDM4EALDH1A1LMNATKT
SCHEMBL23094501 0.78 LMNA (0.50) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL21713021 0.78 KDM4E (0.46) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL11325842 0.77 LMNA (0.41) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL14677401 0.77 LMNA (0.46) KDM4EALDH1A1LMNATKT
SCHEMBL2118802 0.77 LMNA (0.41) KDM4EALDH1A1HPGDHSD17B10LMNA
Hydrochloric Acid SCHEMBL6520994 0.77 LMNA (0.59) KDM4EALDH1A1LMNATKT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197337-A1 CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-06-19 US claimed
WO-2025128424-A1 CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-06-19 WO claimed
CN-115109761-A Isopentenyl transferases and uses thereof 中国科学院分子植物科学卓越创新中心 2022-09-27 CN claimed
CN-113322045-B Polythiol modified polyurethane-polythiourethane bonding material 北京大学 2022-08-26 CN claimed
US-20250197337-A1 CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-06-19 US disclosed
WO-2025128424-A1 CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-06-19 WO disclosed
WO-2025043213-A3 THERAPEUTIC COMPOUNDS AND METHODS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-05-08 WO disclosed
CN-119912730-A High-strength high-toughness cellulose-based bioplastic, preparation method and application 江南大学 2025-05-02 CN disclosed
WO-2025043213-A2 THERAPEUTIC COMPOUNDS AND METHODS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-02-27 WO disclosed
WO-2025043213-A2 THERAPEUTIC COMPOUNDS AND METHODS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-02-27 WO disclosed
CN-119464141-A Culture medium for rapidly culturing psychrophilic bacteria in cow milk and preparation method thereof 上海市农产品质量安全中心 2025-02-18 CN disclosed
US-20250037787-A1 CONCENTRATION BOUNDS IN LARGE NETWORKS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-30 US disclosed
US-8268848-B2 Cyclopropane compound EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-09-18 US disclosed
US-20120095031-A1 CYCLOPROPANE COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-04-19 US disclosed
US-20120095031-A1 CYCLOPROPANE COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-04-19 US disclosed
US-20120095031-A1 CYCLOPROPANE COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-04-19 US disclosed
EP-0873317-B1 PYRIMIDIN DERIVATIVES HOFFMANN LA ROCHE (CH) 2001-04-11 EP disclosed
EP-0873317-A1 PYRIMIDIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1998-10-28 EP disclosed
US-5688798-A PSYCHOTIC ILLNESS SUCH AS SCHIZOPHRENIA HOFFMANN-LA ROCHE INC. (US) 1997-11-18 US disclosed
WO-1997013759-A1 PYRIMIDIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1997-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095031-A1 CYCLOPROPANE COMPOUND HCRTR1, HCRTR2, CNR1 KDM4E 1932/4885ALDH1A1 2708/4885HPGD 2630/4885
US-20250197337-A1 CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE STS, BPHL, HPD KDM4E 1235/4885ALDH1A1 731/4885HPGD 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.