Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941537 | 0.90 | FAAH (0.51) | FAAHMGLLBCHE | |
| SCHEMBL23818373 | 0.89 | FAAH (0.51) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL15597354 | 0.85 | FAAH (0.46) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL20811742 | 0.81 | FAAH (0.44) | FAAHMGLLBCHE | |
| SCHEMBL20327258 | 0.79 | FAAH (0.40) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL24529020 | 0.75 | FAAH (0.37) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL13160507 | 0.74 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13941402 | 0.74 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13431057 | 0.74 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL21697211 | 0.72 | F7 (0.42) | FAAHMGLLBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148055-A9 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019148055-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-08-01 | — | — | WO | disclosed |