Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15597354 | 0.90 | FAAH (0.46) | FAAHMGLLBCHE | |
| SCHEMBL13941537 | 0.90 | FAAH (0.51) | FAAHMGLLBCHE | |
| SCHEMBL23818373 | 0.84 | FAAH (0.51) | FAAHMGLLBCHE | |
| SCHEMBL20327258 | 0.81 | FAAH (0.40) | FAAHMGLLBCHE | |
| SCHEMBL21207962 | 0.81 | FAAH (0.46) | FAAHMGLLBCHE | |
| SCHEMBL13431057 | 0.80 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13941402 | 0.80 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13160507 | 0.80 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL24529020 | 0.77 | FAAH (0.37) | FAAHMGLLBCHE | |
| SCHEMBL13941399 | 0.77 | NPC1 (0.54) | FAAHMGLLBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076541-A1 | HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076541-A1 | HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | CRBN, MDM2, STUB1 | FAAH 2512/4885MGLL 2684/4885BCHE 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.