Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15597354 | 0.84 | FAAH (0.46) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL13941537 | 0.79 | FAAH (0.51) | FAAHMGLLBCHE | |
| SCHEMBL21697211 | 0.79 | F7 (0.42) | FAAHMGLLBCHEF7 | |
| SCHEMBL23818373 | 0.78 | FAAH (0.51) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL20327258 | 0.77 | FAAH (0.40) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL20811742 | 0.77 | FAAH (0.44) | FAAHMGLLBCHE | |
| SCHEMBL21207962 | 0.75 | FAAH (0.46) | FAAHMGLLBCHEMEN1KMT2A | |
| SCHEMBL13431057 | 0.70 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13160507 | 0.70 | PLK4 (0.57) | FAAHMGLLBCHE | |
| SCHEMBL13941402 | 0.70 | PLK4 (0.57) | FAAHMGLLBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129925-A1 | NOVEL BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |