Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 6/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254903 | 0.81 | KDM4E (0.49) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL21208517 | 0.74 | HPGD (0.40) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL21208437 | 0.71 | ZAP70 (0.41) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL14496087 | 0.70 | BCL2 (0.46) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL19786607 | 0.69 | TYMS (0.60) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL20821410 | 0.65 | KDM4E (0.55) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL13425232 | 0.64 | RPA1 (0.49) | HPGDKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21208480 | 0.64 | TYMS (0.47) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL14643519 | 0.64 | HPGD (0.48) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL19960369 | 0.64 | HPGD (0.58) | HPGDKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975076-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975076-B2 | Compositions, uses and methods for making them | BAX, CASP3, CASP7 | HPGD 635/4885KDM4E 1957/4885ALDH1A1 1878/4885 |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | HPGD 426/4885KDM4E 2839/4885ALDH1A1 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.