SCHEMBL21211399

SCHEMBL21211399

CC(C)(C)OC(=O)N1CC2(CC2)C[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 9/20 0.45
KLK7 P49862 1/20 0.43
CTSL P07711 1/20 0.41
ADAM10 O14672 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22730621 1.00 FKBP1A (0.45) FKBP1AKLK7CTSLADAM10MMP2
SCHEMBL18084468 0.90 KLK7 (0.47) FKBP1AKLK7CTSL
SCHEMBL934333 0.90 KLK7 (0.47) FKBP1AKLK7CTSL
Hydrochloric Acid SCHEMBL26098360 0.89 KLK7 (0.46) FKBP1AKLK7CTSL
Hydrochloric Acid SCHEMBL26098363 0.89 KLK7 (0.46) FKBP1AKLK7CTSL
SCHEMBL16584597 0.88 FKBP1A (0.46) FKBP1AKLK7CTSL
SCHEMBL31614218 0.88 FKBP1A (0.46) FKBP1AKLK7CTSL
SCHEMBL16584596 0.88 FKBP1A (0.46) FKBP1AKLK7CTSL
SCHEMBL20642435 0.87 FKBP1A (0.45) FKBP1AKLK7CTSL
SCHEMBL21441839 0.87 FKBP1A (0.45) FKBP1AKLK7CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605386-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-08-27 EP disclosed
US-20250059171-A1 ANTIVIRAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-02-20 US disclosed
EP-4444711-A1 ANTIVIRAL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2024-10-16 EP disclosed
US-20240182444-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-06 US disclosed
WO-2024086111-A1 ANTI-VIRAL COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2024-04-25 WO disclosed
WO-2023104882-A1 ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2023-06-15 WO disclosed
CN-112047939-B Tetrahydropyridopyrimidine compound with anti-tumor activity 江苏先声药业有限公司 2023-05-02 CN disclosed
US-11078202-B2 β-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-08-03 US disclosed
US-20210046057-A1 Beta-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-02-18 US disclosed
US-20210032260-A1 Beta-lactamase inhibitor and use thereof Evopoint Biosciences Co., Ltd. (CN) 2021-02-04 US disclosed
EP-3744722-A1 ß-LACTAMASE INHIBITOR AND USE THEREOF Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2020-12-02 EP disclosed
WO-2019144912-A1 β-LACTAMASE INHIBITOR AND USE THEREOF 苏州信诺维医药科技有限公司 2019-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032260-A1 Beta-lactamase inhibitor and use thereof CYP51A1, LCT, CEL FKBP1A 1678/4885KLK7 1159/4885CTSL 260/4885
US-11078202-B2 β-lactamase inhibitor and use thereof CYP51A1, LCT, CEL FKBP1A 1610/4885KLK7 1160/4885CTSL 249/4885
US-20240182444-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 FKBP1A 1766/4885KLK7 3296/4885CTSL 1088/4885
US-20210046057-A1 Beta-lactamase inhibitor and use thereof CYP51A1, LCT, CEL FKBP1A 1678/4885KLK7 1159/4885CTSL 260/4885
US-20250059171-A1 ANTIVIRAL COMPOUNDS ZC3HAV1, ACE, EIF2AK2 FKBP1A 586/4885KLK7 818/4885CTSL 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.