Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 7/20 | 0.36 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 3/20 | 0.35 |
| ▸ | CCND1 | P24385 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25711606 | 0.94 | KDM4E (0.40) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL22180550 | 0.94 | KDM4E (0.42) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL30789336 | 0.94 | KDM4E (0.42) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL16625479 | 0.91 | KDM4E (0.38) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL29006767 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL5808357 | 0.85 | KIF11 (0.47) | KIF11PARP14TDO2IDO1CDK4 | |
| SCHEMBL18896081 | 0.85 | BCHE (0.39) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL21375324 | 0.85 | KDM4E (0.46) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL29774746 | 0.84 | KIF11 (0.41) | KDM4EATML3MBTL1KIF11PARP14 | |
| SCHEMBL25207668 | 0.84 | PARP14 (0.46) | KDM4EPARP14TDO2GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190237676-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190237676-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLC18A2, SLC18A1, MAOA | KDM4E 1377/4885ATM 4180/4885L3MBTL1 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.