Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21215774 | 0.93 | NPC1 (0.44) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL21215771 | 0.91 | NPC1 (0.44) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL21215633 | 0.90 | KDM4E (0.50) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL18943871 | 0.89 | NPC1 (0.50) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL21215775 | 0.88 | KDM4E (0.42) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL24475651 | 0.88 | SMN1; SMN2 (0.47) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL21215590 | 0.87 | KDM4E (0.50) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL18943875 | 0.87 | KDM4E (0.53) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL18943873 | 0.87 | PIK3CD (0.50) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL24475740 | 0.86 | PIK3CD (0.47) | NPC1RAB9APOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190233398-A1 | HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190233398-A1 | HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | CRY1, CRY2, PER2 | NPC1 4195/4885RAB9A 3313/4885POLB 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.