Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245480 | 0.83 | GAA (0.36) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2608093 | 0.81 | TSHR (0.33) | GAAALDH1A1TSHRCA2CA4 | |
| SCHEMBL525085 | 0.78 | CA1 (0.48) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27557541 | 0.78 | GAA (0.34) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22112316 | 0.78 | ACHE (0.46) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL12689887 | 0.78 | HDAC1 (0.37) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31026375 | 0.76 | TSHR (0.31) | TSHRCA2NQO2CA1 | |
| SCHEMBL8374077 | 0.76 | CA1 (0.46) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2266180 | 0.76 | CA2 (0.40) | NPSR1TSHRCA2CA4NQO2 | |
| SCHEMBL524143 | 0.74 | CA2 (0.56) | ALDH1A1MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790091-B | Substituted bis (trifluorovinyl) benzene compounds | 东曹精细化工株式会社 | 2021-06-15 | — | — | CN | disclosed |
| EP-3521266-B1 | SUBSTITUTED BIS(TRIFLUOROVINYL)BENZENE COMPOUND | TOSOH FINECHEM CORP (JP) | 2021-03-24 | — | — | EP | disclosed |
| US-10654779-B2 | Substituted bis(trifluorovinyl)benzene compound | TOSOH FINECHEM CORPORATION (JP) | 2020-05-19 | — | — | US | disclosed |
| US-20200017429-A1 | SUBSTITUTED BIS(TRIFLUOROVINYL)BENZENE COMPOUND | TOSOH FINECHEM CORPORATION (JP) | 2020-01-16 | — | — | US | disclosed |
| EP-3521266-A1 | SUBSTITUTED BIS(TRIFLUOROVINYL)BENZENE COMPOUND | Tosoh Finechem Corporation (JP) | 2019-08-07 | — | — | EP | disclosed |
| CN-109790091-A | Replace bis- (trifluoro vinyl) benzene compounds | 东曹精细化工株式会社 | 2019-05-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654779-B2 | Substituted bis(trifluorovinyl)benzene compound | TCF7L2, AFF1, TYR | GAA 726/4885ALDH1A1 1738/4885MEN1 2025/4885 |
| US-20200017429-A1 | SUBSTITUTED BIS(TRIFLUOROVINYL)BENZENE COMPOUND | TCF7L2, AFF1, TYR | GAA 726/4885ALDH1A1 1738/4885MEN1 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.