Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220157 | 1.00 | OPRM1 (0.78) | OPRM1 | |
| SCHEMBL21220156 | 1.00 | OPRM1 (0.78) | OPRM1 | |
| SCHEMBL21238289 | 1.00 | OPRM1 (0.78) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220600 | 0.99 | OPRM1 (0.77) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220603 | 0.99 | OPRM1 (0.77) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220597 | 0.99 | OPRM1 (0.77) | OPRM1 | |
| SCHEMBL21237961 | 0.91 | OPRM1 (0.80) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220178 | 0.90 | OPRM1 (0.78) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220177 | 0.90 | OPRM1 (0.78) | OPRM1 | |
| Hydrochloric Acid SCHEMBL21220179 | 0.90 | OPRM1 (0.78) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033394-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. | 2022-02-03 | — | — | US | disclosed |
| US-11180455-B2 | Compounds for the treatment of pain | ALKERMES, INC. | 2021-11-23 | — | — | US | disclosed |
| CN-111989327-A | Compounds for the treatment of pain | 奥克梅斯公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20200255383-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2020-08-13 | — | — | US | disclosed |
| US-10604489-B2 | Compounds for the treatment of pain | ALKERMES, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190241524-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604489-B2 | Compounds for the treatment of pain | OPRK1, OPRL1, ACHE | OPRM1 7/4885 |
| US-20190241524-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885 |
| US-11180455-B2 | Compounds for the treatment of pain | OPRK1, OPRL1, ACHE | OPRM1 7/4885 |
| US-20220033394-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885 |
| US-20200255383-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | OPRK1, OPRL1, ACHE | OPRM1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.