Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313444 | 0.78 | TYMP (0.52) | TYMP | |
| SCHEMBL855321 | 0.64 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL11733305 | 0.64 | L3MBTL1 (0.63) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7553005 | 0.62 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL20828259 | 0.59 | POLB (0.64) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL17271400 | 0.59 | L3MBTL1 (0.56) | L3MBTL1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL11736849 | 0.58 | KDM4E (0.46) | L3MBTL1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7544489 | 0.57 | CYP1A2 (0.56) | L3MBTL1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL20828261 | 0.56 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1TYMPSMN1; SMN2LMNA | |
| SCHEMBL9872008 | 0.55 | KDM4E (0.61) | L3MBTL1KDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2690178-B1 | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same | UNIV OKLAHOMA (US) | 2021-12-22 | — | — | EP | disclosed |
| US-20160053290-A1 | Production of Defined Monodisperse Heparosan Polymers and Unnatural Polymers with Polysaccharide Synthases | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2016-02-25 | — | — | US | disclosed |
| US-9200024-B2 | Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-12-01 | — | — | US | disclosed |
| EP-2690178-A1 | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same | The Board Of Regents Of The University Of Oklahoma (US) | 2014-01-29 | — | — | EP | disclosed |
| US-20120108802-A1 | PRODUCTION OF DEFINED MONODISPERSE HEPAROSAN POLYMERS AND UNNATURAL POLYMERS WITH POLYSACCHARIDE SYNTHASES | DEANGELIS PAUL L (US) | 2012-05-03 | — | — | US | disclosed |
| US-8088604-B2 | Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2012-01-03 | — | — | US | disclosed |
| US-7741091-B2 | Methods of producing hyaluronic acid and chimeric and hybrid glycosaminoglycan polymers | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2010-06-22 | — | — | US | disclosed |
| US-7579173-B2 | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using the same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-08-25 | — | — | US | disclosed |
| US-7575904-B2 | Using the hyaluronate synthase from Pasteurella multocida; coatings for biomaterials wherein the coatings provide protective properties to the biomaterial and/or act as a bioadhesive; coatings could be applied to electrical devices, sensors, catheters | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-08-18 | — | — | US | disclosed |
| EP-2079846-A2 | TARGETED GLYCOSAMINOGLYCAN POLYMERS BY POLYMER GRAFTING AND METHODS OF MAKING AND USING SAME | The Board Of Rengents Of The University Of Oklahoma (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1575622-A2 | TARGETED GLYCOSAMINOGLYCAN POLYMERS BY POLYMER GRAFTING AND METHODS OF MAKING AND USING SAME | Deangelis, Paul L. (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20050124046-A1 | Polymer grafting by polysaccharide synthases | DEANGELIS PAUL L (US) | 2005-06-09 | — | — | US | disclosed |
| EP-1470235-A2 | GLYCOSAMINOGLYCAN POLYMERS AND METHODS OF MAKING AND USING SAME | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040132143-A1 | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA, THE | 2004-07-08 | — | — | US | disclosed |
| WO-2003029261-A9 | GLYCOSAMINOGLYCAN POLYMERS AND METHODS OF MAKING AND USING SAME | DEANGELIS PAUL L (US) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004032830-A2 | TARGETED GLYCOSAMINOGLYCAN POLYMERS BY POLYMER GRAFTING AND METHODS OF MAKING AND USING SAME | UNIVERSITY OF OKLAHOMA (US) | 2004-04-22 | — | — | WO | disclosed |
| US-20030077763-A1 | Polymer grafting by polysaccharide synthases | DEANGELIS PAUL L (US) | 2003-04-24 | — | — | US | disclosed |
| WO-2003029261-A2 | GLYCOSAMINOGLYCAN POLYMERS AND METHODS OF MAKING AND USING SAME | DEANGELIS PAUL L (US) | 2003-04-10 | — | — | WO | disclosed |
| US-6444447-B1 | USING THE HYALURONATE SYNTHASE FROM PASTEURELLA MULTOCIDA FOR GRAFTING, COATING FOR BIOMATERIALS | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2002-09-03 | — | — | US | disclosed |
| WO-2000027437-A9 | POLYMER GRAFTING BY POLYSACCHARIDE SYNTHASES | UNIV OKLAHOMA (US) | 2001-06-28 | — | — | WO | disclosed |