Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961721 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL276284 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL11652356 | 0.77 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL7553005 | 0.76 | L3MBTL1 (0.43) | CYP2C19HPGDALDH1A1L3MBTL1KMT2A | |
| SCHEMBL20944445 | 0.74 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL7544947 | 0.73 | ALDH1A1 (0.50) | CYP1A2CYP2C19HPGDALDH1A1L3MBTL1 | |
| SCHEMBL7546356 | 0.72 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL7046856 | 0.72 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL2565795 | 0.72 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL23204027 | 0.71 | CYP1A2 (0.76) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |