SCHEMBL7553005

SCHEMBL7553005

Cc1c(C(=O)O)[nH]c(=S)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
KDM3B Q7LBC6 1/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
GAA P10253 3/20 0.40
MAPT P10636 2/20 0.40
PKM P14618 1/20 0.40
BRPF1 P55201 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTK2 Q05397 1/20 0.40
CYP2C19 P33261 1/20 0.38
GPR35 Q9HC97 1/20 0.36
JAK2 O60674 1/20 0.35
THRB P10828 1/20 0.35
NSD2 O96028 1/20 0.35
CASP6 P55212 1/20 0.35
LMNA P02545 1/20 0.35
RXFP1 Q9HBX9 1/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2894307 0.78 JAK2 (0.57) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL20577753 0.77 CYP2C19 (0.44) L3MBTL1KDM3BKDM4EALDH1A1GAA
SCHEMBL7544489 0.76 CYP1A2 (0.56) L3MBTL1ALDH1A1GAAMAPTTDP1
SCHEMBL31495905 0.71 GPR35 (0.45) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL29955374 0.69 PTK2 (0.36) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL11736823 0.67 TYMP (0.60) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL7544529 0.67 LGMN (0.37) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL3156800 0.66 CYP1A2 (0.54) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL855321 0.64 L3MBTL1 (0.44) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL11733305 0.64 L3MBTL1 (0.63) L3MBTL1KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802194-B1 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORP (JP) 2002-06-19 EP disclosed
US-5795497-A Thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1998-08-18 US disclosed
EP-0802194-A2 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1997-10-22 EP disclosed