SCHEMBL2122579

SCHEMBL2122579

O=S(=O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 2/20 1.00
MAPK1 P28482 1/20 1.00
MEN1 O00255 1/20 0.76
KMT2A Q03164 1/20 0.76
KDM4E B2RXH2 2/20 0.67
HPGD P15428 1/20 0.67
ALOX15 P16050 1/20 0.67
HSD17B10 Q99714 1/20 0.67
CA1 P00915 4/20 0.62
CA2 P00918 4/20 0.62
CA12 O43570 3/20 0.62
CA3 P07451 3/20 0.62
CA4 P22748 3/20 0.62
CA6 P23280 3/20 0.62
CA5A P35218 3/20 0.62
CA7 P43166 3/20 0.62
CA9 Q16790 3/20 0.62
CA13 Q8N1Q1 3/20 0.62
CA14 Q9ULX7 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313173 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328031 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL16713293 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5028733 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL7202895 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL1024710 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11589601 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5524377 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11590997 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4045514-B1 RENEWABLE MONOMER AND POLYMER THEREOF ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2025-02-19 EP claimed
EP-1640067-B1 Method for preparing aromatic polyethers using phosphazenium salt phase transfer catalysts SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-17 EP claimed
EP-1078947-B1 Hydrophile polyethersulfones and process for their preparation MEMBRANA GMBH (DE) 2008-02-27 EP claimed
EP-1242503-B1 METHOD FOR ISOLATING DIHYDROXYBIPHENYL POLYETHERSULFONES GEN ELECTRIC (US) 2006-04-12 EP claimed
EP-0686085-B1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 2001-04-04 EP claimed
EP-1078947-A1 Hydrophile polyethersulfones and process for their preparation Akzo Nobel N.V. (NL) 2001-02-28 EP claimed
EP-0381049-B1 PROCESS FOR THE PREPARATION OF BIS-4-CHLOROPHENYL SULFONE BASF Aktiengesellschaft (DE) 1993-06-09 EP claimed
EP-0234223-B1 METHOD FOR THE PREPARATION OF AROMATIC BLOCK COPOLYETHERS BASF Aktiengesellschaft (DE) 1993-04-07 EP claimed
EP-0361131-B1 THERMOPLASTIC MOULDING COMPOSITIONS OF AROMATIC POLYETHER SULFONE AND HYDROGENATED NITRILE RUBBER BAYER AG (DE) 1993-01-20 EP claimed
EP-0381045-A2 Process for the preparation of Bis-(4-chlorophenyl)-sulfon BASF Aktiengesellschaft (DE) 1990-08-08 EP claimed
EP-0361131-A1 Thermoplastic moulding compositions of aromatic polyether sulfone and hydrogenated nitrile rubber BAYER AG (DE) 1990-04-04 EP claimed
EP-0147708-B1 POLYARYL ETHERS CONTAINING BRANCHED, HIGH MOLECULAR WEIGHT THERMOPLASTIC NITRILE GROUPS, AND THEIR PREPARATION BASF Aktiengesellschaft (DE) 1989-04-19 EP claimed
EP-0234223-A2 Method for the preparation of aromatic block copolyethers BASF Aktiengesellschaft (DE) 1987-09-02 EP claimed
EP-0185237-A1 Thermoplastic moulding compositions BASF Aktiengesellschaft (DE) 1986-06-25 EP claimed
EP-0147708-A2 Polyaryl ethers containing branched, high molecular weight thermoplastic nitrile groups, and their preparation BASF Aktiengesellschaft (DE) 1985-07-10 EP claimed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP claimed
EP-0135130-A2 Process for the preparation of polyethers BASF Aktiengesellschaft (DE) 1985-03-27 EP claimed
EP-0000361-B1 PROCESS FOR THE PREPARATION OF POLY(PHENYLENE-OXY-PHENYLENE-SULFONE) BASF Aktiengesellschaft (DE) 1984-05-16 EP claimed
EP-0012521-B1 VESICULAR RECORDING MATERIALS AND PROCESS FOR THEIR PRODUCTION BEXFORD LIMITED (GB) 1983-03-23 EP claimed
EP-0000361-A1 Process for the preparation of poly(phenylene-oxy-phenylene-sulfone) BASF Aktiengesellschaft (DE) 1979-01-24 EP claimed