SCHEMBL9313173

SCHEMBL9313173

O=S(=O)(c1ccc(Cl)cc1)c1ccc(S(=O)(=O)c2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 2/20 1.00
MAPK1 P28482 1/20 1.00
MEN1 O00255 1/20 0.76
KMT2A Q03164 1/20 0.76
KDM4E B2RXH2 2/20 0.67
HPGD P15428 1/20 0.67
ALOX15 P16050 1/20 0.67
HSD17B10 Q99714 1/20 0.67
CA1 P00915 4/20 0.62
CA2 P00918 4/20 0.62
CA12 O43570 3/20 0.62
CA3 P07451 3/20 0.62
CA4 P22748 3/20 0.62
CA6 P23280 3/20 0.62
CA5A P35218 3/20 0.62
CA7 P43166 3/20 0.62
CA9 Q16790 3/20 0.62
CA13 Q8N1Q1 3/20 0.62
CA14 Q9ULX7 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2122579 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328031 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL16713293 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5028733 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL7202895 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL1024710 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11589601 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5524377 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11590997 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5286817-A Poly(arylene sulfide)/poly(arylene sulfide sulfone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-02-15 US disclosed
US-5268449-A Containing arylene sulfide and arylene sulfonate segments PHILLIPS PETROLEUM COMPANY (US) 1993-12-07 US disclosed
US-5266674-A Copolymers PHILLIPS PETROLEUM COMPANY (US) 1993-11-30 US disclosed
US-5235034-A Increased melt stability and decreased impurities PHILLIPS PETROLEUM COMPANY (US) 1993-08-10 US disclosed
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US disclosed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US disclosed
US-5147719-A Coatings, impact strength PHILLIPS PETROLEUM COMPANY (US) 1992-09-15 US disclosed
US-5144004-A Heat resistance, selective degradation, reaction of halogen substituted sulfones and sulfoxides and alkali metal sulfides PHILLIPS PETROLEUM COMPANY (US) 1992-09-01 US disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed
US-4517354-A PROTECTIVE COATINGS PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
US-4301274-A BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING PHILLIPS PETROLEUM COMPANY (US) 1981-11-17 US disclosed
EP-0033906-A1 Process for the production of aromatic sulfide/sulfone polymers PHILLIPS PETROLEUM COMPANY (US) 1981-08-19 EP disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed