SCHEMBL4328031

SCHEMBL4328031

O=S(=O)(c1ccc(Cl)cc1)c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 2/20 1.00
MAPK1 P28482 1/20 1.00
MEN1 O00255 1/20 0.76
KMT2A Q03164 1/20 0.76
KDM4E B2RXH2 2/20 0.67
HPGD P15428 1/20 0.67
ALOX15 P16050 1/20 0.67
HSD17B10 Q99714 1/20 0.67
CA1 P00915 4/20 0.62
CA2 P00918 4/20 0.62
CA12 O43570 3/20 0.62
CA3 P07451 3/20 0.62
CA4 P22748 3/20 0.62
CA6 P23280 3/20 0.62
CA5A P35218 3/20 0.62
CA7 P43166 3/20 0.62
CA9 Q16790 3/20 0.62
CA13 Q8N1Q1 3/20 0.62
CA14 Q9ULX7 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313173 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2122579 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL16713293 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5028733 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL7202895 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL1024710 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11589601 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL5524377 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL11590997 0.92 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306602-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-01-17 EP disclosed
US-20230399528-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2023-12-14 US disclosed
CN-116997620-A Powder primer composition 大金工业株式会社 2023-11-03 CN disclosed
WO-2022191049-A1 POWDERY PRIMER COMPOSITION ダイキン工業株式会社 2022-09-15 WO disclosed
US-20090156720-A1 Polyethersulfone-Based Resin Composition and Molded Article Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-18 US disclosed
US-20030004302-A1 Process for producing purified polyether sulfones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-02 US disclosed
EP-0411625-B1 Method to produce poly(arylene sulfide/sulfone) polymer PHILLIPS PETROLEUM CO (US) 1996-05-08 EP disclosed
EP-0431612-B1 Purification of halogenated aromatic sulfones or ketones PHILLIPS PETROLEUM CO (US) 1994-09-28 EP disclosed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5331069-A Method of treating poly(arylene sulfide sulfone) polymers and polymers PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
EP-0001768-B1 PROCESS FOR THE PRODUCTION OF POLYETHERS BASF Aktiengesellschaft (DE) 1981-06-17 EP disclosed
US-4200727-A Manufacture of polyethers from bisphenols and dihalides in the absence of solvent and in the presence of alkali metal carbonate BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
US-4200728-A Manufacture of polyethers from bis-(4-hydroxyphenyl)-sulfone and bis-(4-chlorophenyl)-sulfone in N-methylpyrrolidone using an alkali metal carbonate as catalysts BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
EP-0001768-A1 Process for the production of polyethers BASF Aktiengesellschaft (DE) 1979-05-16 EP disclosed
EP-0000361-A1 Process for the preparation of poly(phenylene-oxy-phenylene-sulfone) BASF Aktiengesellschaft (DE) 1979-01-24 EP disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed