Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23869937 | 0.81 | L3MBTL1 (0.53) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL371042 | 0.75 | L3MBTL1 (0.74) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL25054533 | 0.74 | MEN1 (0.49) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL19023810 | 0.72 | KMT2A (0.61) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL14603340 | 0.72 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL17720978 | 0.72 | L3MBTL1 (0.70) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL75848 | 0.72 | L3MBTL1 (0.70) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6112014 | 0.72 | L3MBTL1 (0.70) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL18212420 | 0.72 | L3MBTL1 (0.70) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7646098 | 0.71 | S1PR1 (0.66) | L3MBTL1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200295270-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | L3MBTL1 1480/4885LMNA 3497/4885KMT2A 1267/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | L3MBTL1 1480/4885LMNA 3497/4885KMT2A 1267/4885 |
| US-20200295270-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | L3MBTL1 2186/4885LMNA 2573/4885KMT2A 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.