Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.66 |
| ▸ | QDPR | P09417 | 3/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914651 | 1.00 | HTR2C (0.66) | HTR2CQDPRSIGMAR1PIK3CDESR1 | |
| SCHEMBL10354111 | 0.82 | HSD17B1 (0.47) | HTR2CQDPRSIGMAR1PIK3CDESR1 | |
| Hydrochloric Acid SCHEMBL11019773 | 0.81 | PIK3CD (0.46) | HTR2CQDPRSIGMAR1PIK3CDESR1 | |
| SCHEMBL4791120 | 0.81 | SIGMAR1 (0.79) | HTR2CQDPRSIGMAR1 | |
| SCHEMBL8380936 | 0.80 | QDPR (1.00) | HTR2CQDPRSIGMAR1ESR1ESR2 | |
| SCHEMBL30431801 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1 | |
| SCHEMBL4789465 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4793458 | 0.79 | HTR2C (0.79) | HTR2CQDPRSIGMAR1 | |
| SCHEMBL4510248 | 0.79 | HTR2C (1.00) | HTR2CQDPRSIGMAR1 | |
| SCHEMBL4790435 | 0.79 | HTR2C (0.66) | HTR2CQDPRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526455-A1 | COMPOSITIONS AND METHODS FOR INDUCIBLE ALTERNATIVE SPLICING REGULATION OF GENE EXPRESSION | The Children's Hospital of Philadelphia (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2024186892-A2 | REGULATED CONTROL OF RNA INTERFERENCE BY ALTERNATIVE SPLICING | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2023225160-A1 | COMPOSITIONS AND METHODS FOR INDUCIBLE ALTERNATIVE SPLICING REGULATION OF GENE EXPRESSION | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2023-11-23 | — | — | WO | disclosed |
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |
| EP-4103717-A1 | COMPOSITIONS AND METHODS FOR INDUCIBLE ALTERNATIVE SPLICING REGULATION OF GENE EXPRESSION | The Children's Hospital of Philadelphia (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-111094300-B | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-111094300-A | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2020-05-01 | — | — | CN | disclosed |
| WO-2019149205-A1 | BENZOHETEROARYL DERIVATIVE AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2019-08-08 | — | — | WO | disclosed |