Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21228623 | 0.83 | NPC1 (0.49) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL21220022 | 0.79 | LMNA (0.40) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL21220012 | 0.78 | LMNA (0.38) | LMNAESR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL21220014 | 0.76 | LMNA (0.38) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL21228671 | 0.75 | LMNA (0.36) | LMNAESR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL3851646 | 0.74 | MEN1 (0.59) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL12590771 | 0.74 | LMNA (0.45) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL21228640 | 0.73 | LMNA (0.35) | LMNAESR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL16268846 | 0.72 | ESR1 (0.44) | LMNAESR1TSHRCYP1A2CYP2C19 | |
| SCHEMBL28781530 | 0.72 | L3MBTL1 (0.43) | LMNAESR1TSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |