Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220022 | 0.83 | LMNA (0.40) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21220014 | 0.82 | LMNA (0.38) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21228643 | 0.81 | ALDH1A1 (0.39) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21220012 | 0.81 | LMNA (0.38) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21228671 | 0.80 | LMNA (0.36) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21228701 | 0.78 | PTGES (0.37) | LMNATSHRMAPK1GAATP53 | |
| SCHEMBL21228623 | 0.77 | NPC1 (0.49) | LMNATSHRMAPK1MAPTL3MBTL1 | |
| SCHEMBL21220004 | 0.77 | NPC1 (0.43) | LMNATSHRMAPK1MAPTATM | |
| SCHEMBL21228625 | 0.76 | ABCB11 (0.35) | LMNATSHRMAPK1HCAR3 | |
| SCHEMBL21228619 | 0.73 | LMNA (0.46) | LMNATSHRMAPK1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |