Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948657 | 0.82 | — | — | |
| Phosphoric Acid SCHEMBL7631550 | 0.78 | CA2 (0.46) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL19031806 | 0.76 | TP53 (0.47) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL15541024 | 0.76 | LAP3 (0.43) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL28196139 | 0.76 | TP53 (0.47) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL5901916 | 0.73 | CA2 (0.50) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL571124 | 0.73 | CA2 (0.50) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL15540730 | 0.73 | CA2 (0.50) | LAP3CA2CA12CA1MMP1 | |
| Benzene SCHEMBL28378011 | 0.72 | CA2 (0.40) | LAP3CA2CA12CA1MMP1 | |
| Phosphoric Acid SCHEMBL22235268 | 0.70 | CA2 (0.46) | LAP3CA2MMP2PEPDPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443244-A1 | IMPROVED ISOPRENE PRODUCTION USING THE DXP AND MVA PATHWAY | Danisco US Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010148150-A1 | IMPROVED ISOPRENE PRODUCTION USING THE DXP AND MVA PATHWAY | DANISCO US INC. (US) | 2010-12-23 | — | — | WO | disclosed |