Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22373594 | 0.90 | CES2 (0.52) | SMN1; SMN2MAPTALDH1A1L3MBTL1CES2 | |
| SCHEMBL26294470 | 0.87 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1CES2CES1 | |
| SCHEMBL22765129 | 0.81 | CES2 (0.54) | SMN1; SMN2MAPTALDH1A1L3MBTL1GSK3B | |
| SCHEMBL23864293 | 0.81 | CES2 (0.54) | SMN1; SMN2MAPTALDH1A1USP2L3MBTL1 | |
| SCHEMBL18869777 | 0.80 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL18533575 | 0.79 | CES2 (0.48) | SMN1; SMN2MAPTALDH1A1L3MBTL1CES2 | |
| Bicarbonate SCHEMBL9521282 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTALDH1A1KDM4EUSP2 | |
| Biphenyl SCHEMBL27937078 | 0.78 | CES2 (0.56) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL8215241 | 0.78 | POLB (0.50) | SMN1; SMN2MAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL18537213 | 0.77 | RAB9A (0.51) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225645-B1 | PHOTOACTIVE ADDITIVES WITH PHOTOACTIVE MONOMERS AND ENDCAPS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-08-07 | — | — | EP | disclosed |