Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823292 | 0.98 | SIRT2 (0.41) | SIRT2SIRT1SIRT3ROCK2SIRT5 | |
| SCHEMBL18823291 | 0.98 | SIRT2 (0.41) | SIRT2SIRT1SIRT3ROCK2SIRT5 | |
| SCHEMBL25830938 | 0.94 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5NPY1R | |
| SCHEMBL25009841 | 0.93 | SIRT2 (0.42) | SIRT2SIRT1SIRT3ROCK2SIRT5 | |
| SCHEMBL20864058 | 0.93 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5FURIN | |
| SCHEMBL24335319 | 0.92 | SIRT2 (0.42) | SIRT2SIRT1SIRT3ROCK2SIRT5 | |
| SCHEMBL18914850 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3ROCK2SIRT5 | |
| SCHEMBL23330252 | 0.92 | SIRT2 (0.40) | SIRT2SIRT1SIRT3SIRT5NPY1R | |
| SCHEMBL23106472 | 0.92 | SIRT2 (0.40) | SIRT2SIRT1SIRT3SIRT5NPY1R | |
| SCHEMBL25615822 | 0.92 | SIRT5 (0.41) | SIRT2SIRT1SIRT3SIRT5CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC | 2023-06-15 | — | — | US | disclosed |
| US-20190241649-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241649-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | SIRT2 2841/4885SIRT1 2541/4885SIRT3 2417/4885 |
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | SIRT2 2841/4885SIRT1 2541/4885SIRT3 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.