Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387330 | 0.98 | SIRT5 (0.38) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL18823533 | 0.94 | CHRNA1 (0.38) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL21230049 | 0.92 | SIRT2 (0.43) | SIRT5SIRT2SIRT1SIRT3CPB1 | |
| SCHEMBL25000070 | 0.91 | SIRT2 (0.38) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL20616683 | 0.91 | SIRT5 (0.38) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL20616684 | 0.91 | SIRT5 (0.38) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL25826705 | 0.90 | FURIN (0.37) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL18823291 | 0.89 | SIRT2 (0.41) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL18823292 | 0.89 | SIRT2 (0.41) | SIRT5SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL19687790 | 0.89 | SIRT5 (0.39) | SIRT5SIRT2SIRT1SIRT3FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | SIRT5 2313/4885SIRT2 2841/4885SIRT1 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.