Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23766332 | 0.81 | POLB (0.36) | SOAT1 | |
| SCHEMBL25659178 | 0.79 | L3MBTL1 (0.41) | — | |
| SCHEMBL5033173 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL30641414 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL6685019 | 0.71 | TSHR (0.45) | SOAT1 | |
| SCHEMBL199520 | 0.70 | POLB (0.37) | SOAT1 | |
| SCHEMBL6859719 | 0.69 | CSNK1E (0.39) | — | |
| SCHEMBL2273443 | 0.69 | — | — | |
| SCHEMBL199521 | 0.69 | GABRA1 (0.50) | SOAT1 | |
| SCHEMBL29183951 | 0.68 | CSNK1E (0.41) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019150305-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2019-08-08 | — | — | WO | disclosed |