Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9154692 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6892150 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL9311863 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL3131682 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6894372 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL9173529 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL1134616 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL10361962 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL2812471 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL27992053 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536035-B | Preparation method of temperature-resistant organic bentonite, temperature-resistant organic bentonite and application thereof | 中石化南京化工研究院有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117106328-A | Organic bentonite, and preparation method and application thereof | 阳原县仁恒精细粘土有限责任公司 | 2023-11-24 | — | — | CN | claimed |
| CN-115536035-A | Preparation method of temperature-resistant organic bentonite, temperature-resistant organic bentonite and application thereof | 中石化南京化工研究院有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-109957170-B | Nano modified flame-retardant master batch and low-smoke flame-retardant PBT (polybutylene terephthalate) composite material | 江西固康新材料有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-113637350-A | Preparation process of easily dispersible organic bentonite in high-polarity solvent system | 杭州海迪斯新材料有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-108102349-B | Preparation method of organic bentonite/epoxy resin composite modified waterborne polyurethane emulsion | 南京理工大学 | 2020-06-30 | — | — | CN | claimed |
| EP-1812149-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER | TORAY INDUSTRIES (JP) | 2013-06-12 | — | — | EP | claimed |
| EP-3550030-B1 | METHOD FOR MEASURING GLYCATION RATE OF HEMOGLOBIN | TOYO BOSEKI (JP) | 2025-01-01 | — | — | EP | disclosed |
| CN-118385602-A | Silver powder preparation method with pore structure inside spherical particles | 深圳市惟楚新材料有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-115536035-B | Preparation method of temperature-resistant organic bentonite, temperature-resistant organic bentonite and application thereof | 中石化南京化工研究院有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115536035-B | Preparation method of temperature-resistant organic bentonite, temperature-resistant organic bentonite and application thereof | 中石化南京化工研究院有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117106328-A | Organic bentonite, and preparation method and application thereof | 阳原县仁恒精细粘土有限责任公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230219251-A1 | MULTIFUNCTIONAL WOOD PRESERVATIVE COMPOSITION AND WOOD PRESERVATION TREATMENT METHOD USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-07-13 | — | — | US | disclosed |
| CN-1789985-A | Oxygen detection body | MITSUBISHI GAS CHEMICAL CO (JP) | 2006-06-21 | — | — | CN | disclosed |
| WO-2006051888-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-18 | — | — | WO | disclosed |
| CN-1708279-A | Glossy anti-migration composition comprising a block polymer | OREAL (FR) | 2005-12-14 | — | — | CN | disclosed |
| CN-1700903-A | Composition containing block polymer and gelling agent | OREAL (FR) | 2005-11-23 | — | — | CN | disclosed |
| US-20050095213-A1 | Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product | L'OREAL S.A. (FR) | 2005-05-05 | — | — | US | disclosed |
| US-20040029758-A1 | Method of circulating water in circulatory water tank system and liquid composition for sterilizing and disinfecting circulatory water tank system | LEGIOTEC CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| CN-1240127-A | Spirulina shampoo and productive method thereof | PHARMACEUTICAL FACTORY OF GUAN (CN) | 2000-01-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050095213-A1 | Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product | CUTA, PRKACB, PRKDC | CHRM2 4445/4885CHRM1 4288/4885CHRM3 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.