Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL2387223 | 0.97 | WDR5 (0.64) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL9113005 | 0.97 | WDR5 (0.64) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL10648446 | 0.97 | WDR5 (0.64) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL720475 | 0.97 | WDR5 (0.64) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL28594776 | 0.88 | WDR5 (0.61) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL28765729 | 0.87 | WDR5 (0.54) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL1815228 | 0.87 | WDR5 (0.54) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL2256875 | 0.87 | NQO2 (0.55) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL27879827 | 0.84 | NQO2 (0.53) | WDR5ALDH1A1PRSS1PRSS2PRSS3 | |
| Biphenyl SCHEMBL28438673 | 0.83 | WDR5 (0.86) | WDR5ALDH1A1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4504 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122063148-A | In-situ imaging method for three-dimensional morphology of weld metal small-size inclusion | 陕西工业职业技术大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122037597-A | Low-viscosity high-stability rubber asphalt based on tire reclaimed rubber powder and preparation method thereof | 重庆大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4558558-B1 | A RUBBER COMPOUND MIXTURE | KARGRO RECYCLING B V (NL) | 2026-05-13 | — | — | EP | claimed |
| CN-122011525-A | Ultraviolet-resistant rubber composite material and preparation method thereof | 中国科学院长春应用化学研究所 | 2026-05-12 | — | — | CN | claimed |
| CN-122011963-A | Adhesive film and preparation method and application thereof | 美信新材料股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-121699299-B | Graphene oxide and aramid nanofiber hybridized modified chopped fiber reinforced flexible polymer heat protection material and preparation method and application thereof | 四川大学 | 2026-05-12 | — | — | CN | claimed |
| EP-3898825-B1 | CAPSULES COMPRISING VULCANISATION ACCELERANT AGENTS, THEIR PREPARATION AND USE IN THE VULCANISATION OF ELASTOMERIC COMPOUNDS FOR TYRES | PIRELLI (IT) | 2026-04-01 | — | — | EP | claimed |
| US-20260055258-A1 | A RUBBER COMPOUND MIXTURE | KARGRO RECYCLING B V (NL) | 2026-02-26 | — | — | US | claimed |
| EP-4689018-A1 | FUEL ADDITIVE COMPOSITIONS AND METHODS FOR CONTROLLING CARBON DEPOSITS IN AN INTERNAL COMBUSTION ENGINES | Chevron Oronite Company LLC (US) | 2026-02-11 | — | — | EP | claimed |
| US-12540232-B2 | Elastomeric composition reinforced with ground-biochar | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2026-02-03 | — | — | US | claimed |
| EP-0098034-A2 | A process for producing n-phosphonomethylglycine derivatives and herbicidal compounds and compositions prepared thereby | Geshuri Laboratories Ltd. (IL) | 1984-01-11 | — | — | EP | claimed |
| EP-0006698-B1 | CURABLE POLYSULFIDE POLYMER COMPOSITION AND PROCESS FOR THE PREPARATION OF A SHAPED ARTICLE THEREFROM | THIOKOL CORPORATION (US) | 1983-05-04 | — | — | EP | claimed |
| EP-0006834-B1 | A PROCESS OF RECLAIMING RUBBER | TRELLEBORG AB (SE) | 1982-02-17 | — | — | EP | claimed |
| US-4314920-A | Polysulfide rubbers suitable for hot application | THIOKOL CORPORATION (US) | 1982-02-09 | — | — | US | claimed |
| US-4264481-A | Process of reclaiming rubber | TRELLEBORG AB (SE) | 1981-04-28 | — | — | US | claimed |
| US-4263078-A | HEATING, EXTRUDING WITH SULFUR-CONTAINING ACCELERATORS | THIOKOL CORPORATION (US) | 1981-04-21 | — | — | US | claimed |
| EP-0006834-A2 | A process of reclaiming rubber | TRELLEBORG AB (SE) | 1980-01-09 | — | — | EP | claimed |
| EP-0006698-A1 | Curable polysulfide polymer composition and process for the preparation of a shaped article therefrom | THIOKOL CORPORATION (US) | 1980-01-09 | — | — | EP | claimed |
| US-4003843-A | SILANE, THIAZOLE, GUANIDINE, THIURAM | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | claimed |
| US-3935012-A | Photosensitive sheet materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-01-27 | — | — | US | claimed |