Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952436 | 0.77 | IDO1 (0.37) | IDO1LDLRPCSK9HPGDSHTR2C | |
| SCHEMBL16785552 | 0.75 | IDO1 (0.43) | IDO1LDLRPCSK9HPGDSHTR2C | |
| SCHEMBL21233334 | 0.69 | PIM1 (0.37) | ALDH1A1CYP3A4CYP1A2SMN1; SMN2APOBEC3G | |
| SCHEMBL21233153 | 0.68 | IDO1 (0.47) | IDO1LDLRPCSK9HPGDSHTR6 | |
| SCHEMBL16519361 | 0.68 | IDO1 (0.40) | IDO1LDLRPCSK9HPGDSHTR2C | |
| SCHEMBL30834345 | 0.68 | LDLR (0.41) | IDO1LDLRPCSK9HPGDSPDPK1 | |
| SCHEMBL16202088 | 0.67 | IDO1 (0.50) | IDO1LDLRPCSK9HPGDSHTR2C | |
| SCHEMBL26847505 | 0.67 | CYP11B2 (0.46) | ALDH1A1CYP3A4CYP1A2SMN1; SMN2APOBEC3G | |
| SCHEMBL21233329 | 0.67 | PIM1 (0.41) | ALDH1A1CYP3A4CYP1A2SMN1; SMN2TDP1 | |
| SCHEMBL21233330 | 0.66 | LMNA (0.42) | ALDH1A1CYP3A4CYP1A2SMN1; SMN2APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |