Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KLK3 | P07288 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847505 | 0.81 | CYP11B2 (0.46) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CYP11B1 | |
| SCHEMBL28571375 | 0.78 | PHGDH (0.35) | PIM1PHGDHSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL19145066 | 0.76 | DYRK1A (0.41) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CYP11B1 | |
| SCHEMBL22952404 | 0.76 | PHGDH (0.34) | PIM1PHGDHCYP11B1CYP11B2KLK3 | |
| SCHEMBL26847559 | 0.74 | PARP10 (0.40) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL14996633 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL5280031 | 0.73 | RAB9A (0.51) | PHGDHALDH1A1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL21233326 | 0.72 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2BAZ2B | |
| SCHEMBL21233107 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CYP11B1 | |
| SCHEMBL21233117 | 0.72 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |