Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307933 | 0.94 | TDP1 (0.38) | PTPN1MEN1KMT2ATHRBHDAC3 | |
| SCHEMBL19223309 | 0.88 | PTPN1 (0.35) | PTPN1MEN1KMT2ATHRBHDAC3 | |
| SCHEMBL17307932 | 0.79 | TSHR (0.42) | PTPN1MEN1KMT2ATHRBHDAC3 | |
| SCHEMBL21422384 | 0.78 | PTPN1 (0.48) | PTPN1THRBTSHRTDP1ESR1 | |
| SCHEMBL13567317 | 0.76 | CA1 (0.41) | PTPN1THRBTSHRADRB2ADRB1 | |
| SCHEMBL13577800 | 0.76 | ESR1 (0.47) | PTPN1MEN1KMT2ATHRBTSHR | |
| SCHEMBL21422393 | 0.76 | PTPN1 (0.46) | PTPN1KMT2ATSHRTDP1ALDH1A1 | |
| SCHEMBL8067583 | 0.75 | TSHR (0.49) | THRBTSHRTDP1ALDH1A1 | |
| SCHEMBL19317074 | 0.74 | ADRB2 (0.37) | PTPN1THRBADRB2ADRB1ADRB3 | |
| SCHEMBL822647 | 0.73 | PDCD1 (0.54) | PTPN1TSHRTDP1ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3520765-A1 | RADICALLY CURABLE DENTAL COMPOSITIONS | VOCO GmbH (DE) | 2019-08-07 | — | — | EP | disclosed |