Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422384 | 0.94 | PTPN1 (0.48) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL19316654 | 0.88 | TSHR (0.42) | PDCD1CD274SLC1A5KDM4EPTPN1 | |
| SCHEMBL16351900 | 0.87 | ELANE (0.48) | PDCD1CD274SLC1A5PTPN1MAPT | |
| SCHEMBL21422393 | 0.83 | PTPN1 (0.46) | SMN1; SMN2PTPN1MAPTTSHRELANE | |
| SCHEMBL19157831 | 0.83 | ELANE (0.44) | PDCD1CD274KDM4EPTPN1MAPT | |
| SCHEMBL19316643 | 0.81 | PTPN1 (0.42) | SLC1A5PTPN1TSHRSERPINE1 | |
| SCHEMBL21868937 | 0.80 | TSHR (0.36) | PDCD1CD274SLC1A5SMN1; SMN2PTPN1 | |
| SCHEMBL116940 | 0.80 | KDM4E (0.53) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL9615565 | 0.80 | ALDH1A1 (0.45) | KDM4EESR1TSHRPOLBAPEX1 | |
| SCHEMBL5846246 | 0.79 | PTPN1 (0.48) | KDM4EPTPN1MAPTTSHRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415794-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | Showa Denko K.K. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010361-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | SHOWA DENKO K.K. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010361-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | SHOWA DENKO K.K. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20110294948-A1 | AROMATIC GROUP-CONTAINING (METH) ACRYLATE COMPOUND | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20110294948-A1 | AROMATIC GROUP-CONTAINING (METH) ACRYLATE COMPOUND | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294948-A1 | AROMATIC GROUP-CONTAINING (METH) ACRYLATE COMPOUND | ACR, MMAB, ATR | PDCD1 4335/4885CD274 4447/4885SLC1A5 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.