SCHEMBL21234702

SCHEMBL21234702

COCCOCCN(C)c1cc2cc3cc(/C=C(\C#N)c4nc5ccccc5o4)sc3cc2s1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.42
▸ MEN1 O00255 5/20 0.42
▸ KMT2A Q03164 5/20 0.42
▸ USP2 O75604 1/20 0.42
▸ KDM4E B2RXH2 5/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.42
▸ RAB9A P51151 4/20 0.39
▸ NPC1 O15118 3/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ HTT P42858 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ LMNA P02545 4/20 0.35
▸ HPGD P15428 3/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ GLO1 Q04760 1/20 0.31
▸ BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21234770 0.87 MAPT (0.43) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21234862 0.86 MAPT (0.41) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21234751 0.86 MAPT (0.45) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL24519210 0.85 MAPT (0.40) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21037405 0.80 MAPT (0.46) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21037321 0.78 MAPT (0.42) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21234692 0.75 MAPT (0.45) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL22313932 0.75 MAPT (0.35) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21036844 0.74 MAPT (0.44) MAPTMEN1KMT2AUSP2KDM4E
SCHEMBL21234688 0.71 MEN1 (0.46) MAPTMEN1KMT2AKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365203-B2 Fluorescent dye and preparation method and use thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) 2022-06-21 — — US disclosed
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF DNASE1, POLRMT, DCLRE1B MAPT 2048/4885MEN1 3709/4885KMT2A 3545/4885
US-11365203-B2 Fluorescent dye and preparation method and use thereof DNASE1, POLRMT, DCLRE1B MAPT 2048/4885MEN1 3709/4885KMT2A 3545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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