Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21234751 | 0.90 | MAPT (0.45) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234862 | 0.87 | MAPT (0.41) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234702 | 0.87 | MAPT (0.42) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL24519210 | 0.84 | MAPT (0.40) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234688 | 0.84 | MEN1 (0.46) | MAPTKDM4EKMT2AMEN1RAB9A | |
| SCHEMBL21037405 | 0.84 | MAPT (0.46) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234735 | 0.81 | MAPT (0.39) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234711 | 0.80 | MAPT (0.41) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21234692 | 0.79 | MAPT (0.45) | MAPTKDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL21036844 | 0.78 | MAPT (0.44) | MAPTKDM4ENPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | DNASE1, POLRMT, DCLRE1B | MAPT 2048/4885KDM4E 3930/4885NPSR1 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.