Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213271 | 0.95 | SCD5 (0.34) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL212595 | 0.94 | MAPT (0.34) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL210986 | 0.91 | SCD5 (0.35) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL210927 | 0.90 | KDM4E (0.37) | MAPTRAB9ALMNAL3MBTL1KDM4E | |
| SCHEMBL4350860 | 0.89 | SCD5 (0.35) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL212588 | 0.89 | MAPT (0.34) | MAPTRAB9ALMNAL3MBTL1KDM4E | |
| SCHEMBL210463 | 0.89 | MAPT (0.41) | MAPTRAB9AKDM4EMEN1THRB | |
| SCHEMBL4345650 | 0.88 | MAPT (0.33) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL2841374 | 0.87 | MAOB (0.35) | MAPTRAB9ALMNAL3MBTL1SCD5 | |
| SCHEMBL212860 | 0.87 | KDM4E (0.38) | MAPTRAB9ALMNAL3MBTL1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |