Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756686 | 0.71 | IDH1 (0.40) | SMN1; SMN2 | |
| SCHEMBL18756053 | 0.66 | RAB9A (0.38) | — | |
| SCHEMBL18756583 | 0.62 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2 | |
| SCHEMBL18756126 | 0.59 | GRM2 (0.42) | KDM4ESMN1; SMN2 | |
| SCHEMBL18756168 | 0.58 | CHRM1 (0.45) | — | |
| SCHEMBL21235232 | 0.57 | CHRM1 (0.47) | — | |
| SCHEMBL26129942 | 0.55 | TTR (0.40) | KDM4ESMN1; SMN2 | |
| SCHEMBL4574258 | 0.53 | MAPT (0.44) | SMN1; SMN2 | |
| SCHEMBL23112473 | 0.51 | KDM4E (0.39) | KDM4ESMN1; SMN2 | |
| SCHEMBL17440744 | 0.51 | SMN1; SMN2 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |