SCHEMBL2123541

SCHEMBL2123541

CCOC(=O)C(C)C(=O)Nc1cc(F)cc(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 2/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CASP3 P42574 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
RAB9A P51151 1/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2123271 0.85 MEN1 (0.56) MAPTHTTCA12CA1CA2
SCHEMBL2711405 0.84 MAPT (0.60) MAPTLMNACA12CA1CA2
SCHEMBL2712858 0.83 ALDH1A1 (0.46) MAPTHTTNPSR1LMNACA12
SCHEMBL9416789 0.81 ALDH1A1 (0.46) MAPTHTTNPSR1LMNACA12
SCHEMBL30291840 0.81 MAPT (0.35) MAPTHTTNPSR1LMNACA12
SCHEMBL5016375 0.79 PSEN1 (0.43) GAAKMT2AALDH1A1TSHR
SCHEMBL28067898 0.78 KDM4E (0.60) MAPTHTTNPSR1LMNAKDM4E
SCHEMBL2124402 0.78 KMT2A (0.43) MAPTLMNAKDM4EKMT2AMEN1
SCHEMBL2714959 0.78 TSHR (0.58) MAPTLMNACA12CA1CA2
SCHEMBL2712385 0.77 TSHR (0.45) MAPTHTTNPSR1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12389910-B2 Beta-lactams and their use as herbicides BASF SE (DE) 2025-08-19 US disclosed
US-20240373847-A1 HERBICIDAL MALONAMIDES BASF SE (DE) 2024-11-14 US disclosed
EP-4136071-B1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2024-11-06 EP disclosed
EP-4392403-A1 HERBICIDAL MALONAMIDES BASF SE (DE) 2024-07-03 EP disclosed
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-05-18 US disclosed
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-05-18 US disclosed
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-05-18 US disclosed
WO-2023025854-A1 HERBICIDAL MALONAMIDES BASF SE (DE) 2023-03-02 WO disclosed
EP-4136071-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-02-22 EP disclosed
CN-115279735-A Beta-lactams and their use as herbicides 巴斯夫欧洲公司 2022-11-01 CN disclosed
US-20120094972-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2012-04-19 US disclosed
US-20120094972-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2012-04-19 US disclosed
US-20120094972-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2012-04-19 US disclosed
US-20100331293-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-30 US disclosed
US-20100331293-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-30 US disclosed
US-20100331293-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-30 US disclosed
WO-2010151737-A2 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-29 WO disclosed
WO-2010151737-A2 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-29 WO disclosed
WO-2010151791-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-29 WO disclosed
WO-2010151791-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES POLL, HDHD5, GLRB MAPT 2742/4885HTT 1165/4885NPSR1 3570/4885
US-12389910-B2 Beta-lactams and their use as herbicides POLL, HDHD5, GLRB MAPT 2742/4885HTT 1165/4885NPSR1 3570/4885
US-20240373847-A1 HERBICIDAL MALONAMIDES DDT, ME1, ACE MAPT 1593/4885HTT 623/4885NPSR1 4272/4885
US-20120094972-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, MALT1, BCL9 MAPT 3420/4885HTT 1044/4885NPSR1 2664/4885
US-20100331293-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, MALT1, BCL9 MAPT 3291/4885HTT 1225/4885NPSR1 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.